Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GGT1 | P19440 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317877 | 0.91 | KDM4E (0.58) | KDM4EKMT2AMEN1RECQLTDP1 | |
| SCHEMBL14988689 | 0.90 | KDM4E (0.70) | KDM4EKMT2AMEN1RECQLTDP1 | |
| Diaspirin SCHEMBL40799 | 0.88 | KDM4E (0.75) | KDM4EKMT2AMEN1RECQLTDP1 | |
| Diaspirin SCHEMBL30735506 | 0.88 | KDM4E (0.75) | KDM4EKMT2AMEN1RECQLTDP1 | |
| SCHEMBL3765406 | 0.84 | KDM4E (0.81) | KDM4EKMT2AMEN1RECQLTDP1 | |
| SCHEMBL12446248 | 0.83 | KDM4E (0.69) | KDM4EKMT2AMEN1RECQLTDP1 | |
| SCHEMBL1358287 | 0.83 | KDM4E (0.59) | KDM4EKMT2AMEN1RECQLTDP1 | |
| SCHEMBL13109053 | 0.83 | KDM4E (0.79) | KDM4EKMT2AMEN1RECQLTDP1 | |
| SCHEMBL973615 | 0.83 | KDM4E (0.79) | KDM4EKMT2AMEN1RECQLTDP1 | |
| SCHEMBL14494719 | 0.83 | KDM4E (0.69) | KDM4EKMT2AMEN1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278517-B1 | METHODS FOR IMPROVING SIZE AND APPEARANCE OF A WOUND | AVOCET POLYMER TECHNOLOGIES IN (US) | 2007-05-30 | — | — | EP | claimed |
| US-5281721-A | Substituted carboxy- or carbonyl sulfide-containing 2-benzopyran or 2-benzothiopyran derivatives | GEORGIA TECH RESEARCH CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |
| US-5109018-A | Emphysema therapy | GEORGIA TECH RESEARCH CORPORATION (US) | 1992-04-28 | — | — | US | disclosed |
| US-4596822-A | Chromene or thiochromene ring containing enzyme inhibitor | GEORGIA TECH RESEARCH CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |