Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM1 | P22735 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 7/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617734 | 0.93 | TGM2 (0.39) | TGM2F13A1TGM1SLC1A1SLC1A3 | |
| SCHEMBL30259536 | 0.84 | LTA4H (0.41) | SLC1A1SLC1A3LTA4HSLC15A1 | |
| SCHEMBL36612 | 0.84 | LTA4H (0.41) | SLC1A1SLC1A3LTA4HSLC15A1 | |
| SCHEMBL7314530 | 0.79 | SLC15A1 (0.51) | SLC1A1SLC1A3LTA4HSLC15A1 | |
| SCHEMBL7314517 | 0.79 | SLC15A1 (0.51) | SLC1A1SLC1A3LTA4HSLC15A1 | |
| SCHEMBL26940361 | 0.78 | TGM2 (0.44) | TGM2F13A1TGM1SLC1A1SLC1A3 | |
| SCHEMBL5178314 | 0.78 | CTSB (0.39) | TGM2F13A1TGM1SLC1A1SLC1A3 | |
| SCHEMBL6671876 | 0.77 | SLC15A1 (0.43) | SLC1A1SLC1A3CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10908162 | 0.76 | ANPEP (0.45) | SLC1A1SLC1A3CTSBSLC15A1 | |
| SCHEMBL7619831 | 0.74 | SLC15A1 (0.39) | SLC1A1SLC1A3LTA4HSLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602719-B1 | Control of transglutaminase catalyzed protein modification by selective irreversible transglutaminase inhibitors | N ZYME BIOTEC GMBH (DE) | 2007-06-06 | — | — | EP | claimed |
| EP-1602719-A1 | Control of transglutaminase catalyzed protein modification by selective irreversible transglutaminase inhibitors | N-Zyme BioTec GmbH (DE) | 2005-12-07 | — | — | EP | claimed |
| EP-1600504-A1 | Control of transglutaminase catalyzed protein modification by selective irreversible transglutaminase inhibitors | N-Zyme BioTec GmbH (DE) | 2005-11-30 | — | — | EP | claimed |
| EP-1602719-B1 | Control of transglutaminase catalyzed protein modification by selective irreversible transglutaminase inhibitors | N ZYME BIOTEC GMBH (DE) | 2007-06-06 | — | — | EP | disclosed |
| EP-1602719-A1 | Control of transglutaminase catalyzed protein modification by selective irreversible transglutaminase inhibitors | N-Zyme BioTec GmbH (DE) | 2005-12-07 | — | — | EP | disclosed |
| EP-1600504-A1 | Control of transglutaminase catalyzed protein modification by selective irreversible transglutaminase inhibitors | N-Zyme BioTec GmbH (DE) | 2005-11-30 | — | — | EP | disclosed |