Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 4/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1819616 | 0.87 | NR4A1 (0.69) | NR4A1AKR1C3PBRM1ATMCDC25B | |
| SCHEMBL5962987 | 0.86 | AKR1C3 (0.62) | NR4A1AKR1C3GAAPBRM1ATM | |
| SCHEMBL21247044 | 0.85 | AKR1C3 (0.55) | NR4A1AKR1C3GAAATMCDC25B | |
| SCHEMBL609880 | 0.84 | GAA (0.54) | RORCGAAATMTSHRALDH1A1 | |
| SCHEMBL9725353 | 0.82 | TSHR (0.57) | NR4A1AKR1C3PBRM1CDC25BTSHR | |
| SCHEMBL29375774 | 0.81 | KMT2A (0.62) | NR4A1ALDH1A1POLBKMT2ALMNA | |
| SCHEMBL333687 | 0.81 | KMT2A (0.62) | NR4A1ALDH1A1POLBKMT2ALMNA | |
| Benzene SCHEMBL28318261 | 0.80 | AKR1C3 (0.61) | NR4A1AKR1C3GAAATMCDC25B | |
| SCHEMBL503678 | 0.79 | AKR1C3 (0.73) | NR4A1AKR1C3GAAATMCDC25B | |
| SCHEMBL8956729 | 0.79 | KMT2A (0.44) | ATMALDH1A1POLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1277726-B1 | PROCESS FOR THE PREPARATION OF 2-HALOBENZOIC ACIDS | NIHON NOHYAKU CO LTD (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-7057067-B2 | Process for the preparation of 2-halobenzoic acids | NIHON NOHYAKU CO., LTD. (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20030181759-A1 | Process for the preparation of 2-halobenzoic acids | NIHON NOHYAKU CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1277726-A1 | PROCESS FOR THE PREPARATION OF 2-HALOBENZOIC ACIDS | Nihon Nohyaku Co., Ltd. (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181759-A1 | Process for the preparation of 2-halobenzoic acids | HAO2, CBR1, AOC2 | NR4A1 215/4885RORC 1362/4885AKR1C3 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.