Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978443 | 0.80 | MEN1 (0.41) | ALDH1A1MEN1KMT2ANAPRTKCNQ3 | |
| SCHEMBL248240 | 0.80 | MEN1 (0.41) | ALDH1A1MEN1KMT2ANAPRTKCNQ3 | |
| SCHEMBL27311270 | 0.80 | ALDH1A1 (0.37) | ALDH1A1NAPRTKCNQ3KCNQ2KCNE1 | |
| SCHEMBL29909266 | 0.76 | POLB (0.40) | ALDH1A1NAPRTKCNQ3KCNQ2KCNE1 | |
| SCHEMBL77078 | 0.76 | POLB (0.40) | ALDH1A1NAPRTKCNQ3KCNQ2KCNE1 | |
| SCHEMBL31000265 | 0.74 | GCK (0.46) | KCNQ3KCNQ2KCNE1KCNQ1GRM4 | |
| SCHEMBL18053748 | 0.74 | GCK (0.46) | KCNQ3KCNQ2KCNE1KCNQ1GRM4 | |
| SCHEMBL31000262 | 0.74 | GCK (0.46) | KCNQ3KCNQ2KCNE1KCNQ1GRM4 | |
| SCHEMBL12925545 | 0.73 | DGAT1 (0.40) | ALDH1A1DGAT1GAARAB9A | |
| SCHEMBL24746455 | 0.73 | MAPT (0.41) | ALDH1A1MEN1KMT2ANAPRTKCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791811-A1 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2007-06-06 | — | — | EP | disclosed |
| EP-1697301-A2 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2006033446-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2006-03-30 | — | — | WO | disclosed |
| WO-2005061433-A2 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |