SCHEMBL248240

SCHEMBL248240

CC(C)(O)c1ccc(Cl)nc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
ALDH1A1 P00352 2/20 0.41
KCNQ3 O43525 4/20 0.39
KCNQ2 O43526 4/20 0.39
KCNE1 P15382 3/20 0.39
KCNQ1 P51787 3/20 0.39
ADRA2A P08913 2/20 0.38
ADRA2B P18089 2/20 0.38
ADRA2C P18825 2/20 0.38
DGAT1 O75907 2/20 0.38
GRM4 Q14833 1/20 0.36
GAA P10253 1/20 0.36
PIK3CD O00329 1/20 0.36
HSD11B1 P28845 1/20 0.36
POLB P06746 1/20 0.35
BACE1 P56817 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29978443 1.00 MEN1 (0.41) MEN1KMT2ANAPRTALDH1A1KCNQ3
SCHEMBL29909266 0.82 POLB (0.40) NAPRTALDH1A1KCNQ3KCNQ2KCNE1
SCHEMBL77078 0.82 POLB (0.40) NAPRTALDH1A1KCNQ3KCNQ2KCNE1
SCHEMBL31000262 0.80 GCK (0.46) KCNQ3KCNQ2KCNE1KCNQ1GRM4
SCHEMBL5178358 0.80 ALDH1A1 (0.37) MEN1KMT2ANAPRTALDH1A1KCNQ3
SCHEMBL31000265 0.80 GCK (0.46) KCNQ3KCNQ2KCNE1KCNQ1GRM4
SCHEMBL18053748 0.80 GCK (0.46) KCNQ3KCNQ2KCNE1KCNQ1GRM4
SCHEMBL29879160 0.78 KCNQ3 (0.42) NAPRTALDH1A1KCNQ3KCNQ2KCNE1
SCHEMBL9966941 0.78 KCNQ3 (0.42) NAPRTALDH1A1KCNQ3KCNQ2KCNE1
SCHEMBL27311270 0.78 ALDH1A1 (0.37) NAPRTALDH1A1KCNQ3KCNQ2KCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4448492-B1 COMPOSITIONS AND METHODS OF MAKING AND USING SMALL MOLECULES IN THE TREATMENT OF CANCER REGLAGENE INC (US) 2026-03-04 EP disclosed
US-12448368-B2 Indole compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2025-10-21 US disclosed
US-12404242-B2 Compositions and methods for making and using small molecules in the treatment of cancer REGLAGENE, INC. (US) 2025-09-02 US disclosed
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2025-04-17 US disclosed
US-20250109105-A1 COMPOSITIONS AND METHODS FOR MAKING AND USING SMALL MOLECULES IN THE TREATMENT OF CANCER REGLAGENE, INC. 2025-04-03 US disclosed
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2025-03-20 US disclosed
EP-4448492-A1 COMPOSITIONS AND METHODS OF MAKING AND USING SMALL MOLECULES IN THE TREATMENT OF CANCER Reglagene, Inc. (US) 2024-10-23 EP disclosed
EP-3681883-B1 DIPHENYL DERIVATIVES AND USES THEREOF NOVARTIS AG (CH) 2024-02-21 EP disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 US disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 US disclosed
US-20100222325-A1 Inhibitors of Bruton's Tyrosine Kinase BERTHEL STEVEN 2010-09-02 US disclosed
US-20100063054-A1 cMET INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-03-11 US disclosed
US-20100063054-A1 cMET INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-03-11 US disclosed
US-20100063054-A1 cMET INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-03-11 US disclosed
WO-2010019899-A1 cMET INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-02-18 WO disclosed
WO-2010019899-A1 cMET INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-02-18 WO disclosed
US-20040180925-A1 Dipeptidylpeptidase-IV inhibitor KYOWA HAKKO KOGYO CO., LTD. (JP) 2004-09-16 US disclosed
EP-1354882-A1 DIPEPTIDYL PEPTIDASE IV INHIBITOR KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-10-22 EP disclosed
US-4474602-A Substituted pyridyl compounds, herbicidal compositions and method of use THE DOW CHEMICAL COMPANY (US) 1984-10-02 US disclosed
US-4348396-A Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them HOFFMANN-LA ROCHE INC. (US) 1982-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063054-A1 cMET INHIBITORS CEPT1, LCAT, GNMT MEN1 142/4885KMT2A 394/4885NAPRT 223/4885
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 MEN1 2673/4885KMT2A 1683/4885NAPRT 1832/4885
US-20250122176-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 MEN1 2818/4885KMT2A 1853/4885NAPRT 1753/4885
US-20250109105-A1 COMPOSITIONS AND METHODS FOR MAKING AND USING SMALL MOLECULES IN THE TREATMENT OF CANCER CD47, RB1, TP53 MEN1 160/4885KMT2A 700/4885NAPRT 3036/4885
US-20250092021-A9 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 MEN1 2818/4885KMT2A 1853/4885NAPRT 1753/4885
US-12448368-B2 Indole compounds as androgen receptor modulators AR, FSHR, ADRB3 MEN1 2646/4885KMT2A 1758/4885NAPRT 1658/4885
US-20100222325-A1 Inhibitors of Bruton's Tyrosine Kinase BTK, SYK, LYN MEN1 4537/4885KMT2A 2923/4885NAPRT 1961/4885
US-20040180925-A1 Dipeptidylpeptidase-IV inhibitor DPP4, DPP3, DPP9 MEN1 3315/4885KMT2A 4164/4885NAPRT 2275/4885
US-12404242-B2 Compositions and methods for making and using small molecules in the treatment of cancer CD47, RB1, TP53 MEN1 160/4885KMT2A 700/4885NAPRT 3036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.