Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.52 |
| ▸ | MMP9 | P14780 | 7/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | EEF2K | O00418 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31128480 | 0.89 | ADAMTS4 (0.55) | ADAMTS4MMP9MMP8MMP13CASP1 | |
| SCHEMBL713304 | 0.85 | MMP9 (0.61) | ADAMTS4MMP9MMP8MMP13MMP2 | |
| SCHEMBL698080 | 0.85 | MMP9 (0.61) | ADAMTS4MMP9MMP8MMP13MMP2 | |
| SCHEMBL698079 | 0.85 | MMP9 (0.61) | ADAMTS4MMP9MMP8MMP13MMP2 | |
| SCHEMBL8492008 | 0.78 | MMP9 (0.74) | ADAMTS4MMP9MMP8MMP13MMP2 | |
| SCHEMBL8485346 | 0.78 | MMP9 (0.74) | ADAMTS4MMP9MMP8MMP13MMP2 | |
| SCHEMBL31128449 | 0.78 | MMP2 (0.51) | ADAMTS4MMP9MMP8MMP13MMP2 | |
| SCHEMBL28554116 | 0.77 | GAA (0.55) | ADAMTS4MMP9MMP8MMP13MMP2 | |
| SCHEMBL30988968 | 0.77 | GAA (0.55) | ADAMTS4MMP9MMP8MMP13MMP2 | |
| SCHEMBL7376542 | 0.76 | SLC1A3 (0.57) | ADAMTS4MMP9MMP8MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236716-B1 | Methods for making optically active 3-aminopyrrolidine-2,5-dione derivative and optically active 3-aminopyrrolidine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2007-04-11 | — | — | EP | disclosed |
| EP-1236716-A1 | Methods for making optically active 3-aminopyrrolidine-2,5-dione derivative and optically active 3-aminopyrrolidine derivative | TORAY INDUSTRIES, INC. (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6348600-B1 | CYCLIZING OPTICALLY ACTIVE ASPARAGINE ESTER DERIVATIVE OR ACID SALT THEREOF BY DISSOLVING COMPOUND IN SOLVENT | TORAY INDUSTRIES, INC. (JP) | 2002-02-19 | — | — | US | disclosed |