Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362254 | 0.85 | PTGS2 (0.44) | OPRK1OPRM1RENANPEP | |
| SCHEMBL6930389 | 0.81 | MAOB (0.53) | MAOBMAOA | |
| SCHEMBL4416405 | 0.79 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL4416398 | 0.79 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL5614017 | 0.78 | MAOB (0.41) | MAOBMAOA | |
| SCHEMBL1575643 | 0.77 | NPY4R (0.43) | MAOBMAOAPTGER4MCHR1 | |
| SCHEMBL7698946 | 0.76 | PTGER4 (0.53) | CTSKPTGER4CTSBCTSS | |
| SCHEMBL3362259 | 0.76 | OPRK1 (0.39) | CTSKOPRK1OPRM1RENCTSB | |
| SCHEMBL3362251 | 0.76 | OPRK1 (0.39) | CTSKOPRK1OPRM1RENCTSB | |
| SCHEMBL14968961 | 0.75 | PTGER4 (0.51) | CTSKPTGER4CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1039804-A4 | METHOD FOR TREATING FIBROPROLIFERATIVE DISORDERS BY INHIBITORS OF PROTEIN HYDROXYLATION | CORNELL RES FOUNDATION INC (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1039804-A1 | METHOD FOR TREATING FIBROPROLIFERATIVE DISORDERS BY INHIBITORS OF PROTEIN HYDROXYLATION | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-10-04 | — | — | EP | disclosed |
| US-6080766-A | ADMINISTERING TO A PATIENT AN EFFECTIVE AMOUNT OF A HYDROXYPYRROLIDONE COMPOUND TO SUPPRESS THE FORMATION OF COLLAGEN-LIKE SUBSTANCES OR BIOSYNTHESIS OF PROCOLLAGEN | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-06-27 | — | — | US | disclosed |
| US-6046219-A | ADMINISTERING TO THE PATIENT FOR TREATING THE CONDITIONS MEDIATED BY COLLAGEN FORMATION TOGETHER WITH CELL PROLIFERATION A HYDROXYPYRIDINE DERIVATIVE | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-04-04 | — | — | US | disclosed |
| US-5965585-A | SUPPRESSING FORMATION OF COLLAGEN AND COLLAGEN-LIKE SUBSTANCES OR BIOSYNTHESIS OF PROCOLLAGEN IN LIVING SYSTEMS BY ADMINISTERING A HYDROXYPYRIDONE COMPOUND ENZYME INHIBITOR OF PROTEIN HYDROXYLASE; ANTISCARRING AGENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-10-12 | — | — | US | disclosed |
| US-5965586-A | Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-10-12 | — | — | US | disclosed |
| WO-1999030562-A1 | METHOD FOR TREATING FIBROPROLIFERATIVE DISORDERS BY INHIBITORS OF PROTEIN HYDROXYLATION | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| US-5789426-A | SUPPRESSION FORMATION OF COLLAGEN | CORNELL RESEARCH FOUNDATION, INC. (US) | 1998-08-04 | — | — | US | disclosed |