Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PAX2 | Q02962 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181833 | 0.96 | PDE2A (0.34) | PDE2AALDH1A1TSHRKMT2APOLB | |
| SCHEMBL5181332 | 0.94 | ALDH1A1 (0.35) | PDE2AALDH1A1TSHRKMT2APOLB | |
| SCHEMBL5183012 | 0.87 | LMNA (0.34) | PDE2AALDH1A1TSHRKMT2APOLB | |
| SCHEMBL974960 | 0.86 | LMNA (0.36) | PDE2AALDH1A1TSHRKMT2APOLB | |
| SCHEMBL4819802 | 0.86 | LMNA (0.36) | PDE2AALDH1A1TSHRKMT2APOLB | |
| SCHEMBL5179684 | 0.84 | PDE2A (0.38) | PDE2AALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL5180905 | 0.84 | PAX2 (0.37) | PDE2AALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL974937 | 0.84 | KDM1A (0.39) | PDE2AALDH1A1TSHRKMT2APOLB | |
| SCHEMBL81282 | 0.82 | TSHR (0.41) | PDE2AALDH1A1TSHRKMT2APOLB | |
| SCHEMBL14416878 | 0.82 | PDE2A (0.37) | PDE2AALDH1A1TSHRKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828211-A1 | NOVEL TRIAZOLOPYRIMIDINE DERIVATIVES | Syngeta Participations AG (CH) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006066872-A1 | NOVEL TRIAZOLOPYRIMIDINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-29 | — | — | WO | disclosed |