Sugi Predict

Sugi Predict / Compounds / SCHEMBL974937

SCHEMBL974937

SCHEMBL974937

CN1CCN(c2c(-c3c(F)cc(F)cc3F)c(Cl)nc3ncnn23)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ HRH4 Q9H3N8 1/20 0.38
▸ HRH3 Q9Y5N1 1/20 0.38
▸ ALDH1A1 P00352 3/20 0.38
▸ PAX2 Q02962 1/20 0.37
▸ TSHR P16473 4/20 0.36
▸ NPSR1 Q6W5P4 3/20 0.36
▸ GLA P06280 1/20 0.36
▸ KMT2A Q03164 4/20 0.36
▸ MEN1 O00255 3/20 0.36
▸ MAPT P10636 2/20 0.36
▸ HTT P42858 1/20 0.36
▸ APP P05067 3/20 0.36
▸ POLB P06746 1/20 0.35
▸ MAPK1 P28482 2/20 0.35
▸ PDE2A O00408 1/20 0.35
▸ USP2 O75604 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4819802 0.88 LMNA (0.36) SMN1; SMN2ALDH1A1PAX2TSHRNPSR1
SCHEMBL974960 0.88 LMNA (0.36) SMN1; SMN2ALDH1A1PAX2TSHRNPSR1
SCHEMBL5181332 0.87 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1PAX2TSHRNPSR1
SCHEMBL973868 0.87 ALDH1A1 (0.45) KDM1ASMN1; SMN2ALDH1A1PAX2TSHR
SCHEMBL81282 0.86 TSHR (0.41) SMN1; SMN2ALDH1A1TSHRNPSR1GLA
SCHEMBL4817224 0.86 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1PAX2TSHRNPSR1
SCHEMBL14416878 0.86 PDE2A (0.37) SMN1; SMN2ALDH1A1TSHRNPSR1GLA
SCHEMBL5180451 0.84 PDE2A (0.35) SMN1; SMN2ALDH1A1PAX2TSHRNPSR1
SCHEMBL7821613 0.84 PDE2A (0.38) SMN1; SMN2ALDH1A1TSHRNPSR1GLA
SCHEMBL5183012 0.84 LMNA (0.34) SMN1; SMN2ALDH1A1PAX2TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8974806-B2 Method for producing aqueous active substance compositions of active substances that are hardly soluble in water BASF AKTIENGESELLSCHAFT (DE) 2015-03-10 — — US disclosed
US-8741324-B2 Liquid pesticide compositions BASF SE (DE) 2014-06-03 — — US disclosed
US-8728504-B2 Process for solubilizing hydrophobic active ingredients in aqueous medium BASF SE (DE) 2014-05-20 — — US disclosed
EP-2676680-A1 Use of hydrophobin polypeptides as penetration enhancers BASF SE (DE) 2013-12-25 — — EP disclosed
US-8497230-B2 Solid crop protection agents containing polyalkoxylate, method for their production and use thereof BASF AKTIENGESELLSCHAFT (DE) 2013-07-30 — — US disclosed
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF SE (DE) 2013-05-16 — — US disclosed
EP-1763300-B1 USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS BASF SE (DE) 2013-05-15 — — EP disclosed
US-20110312497-A1 USE OF HYDROPHOBIN AS A SPREADING AGENT BASF SE (DE) 2011-12-22 — — US disclosed
US-20110195844-A1 PROCESS FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AQUEOUS MEDIUM BASF SE (DE) 2011-08-11 — — US disclosed
EP-2308460-A1 Composition comprising active agents and at least one nitrogen-containing hyper-branched polymer BASF SE (DE) 2011-04-13 — — EP disclosed
WO-2007048851-A1 SOLID CROP PROTECTION AGENTS CONTAINING POLYALKOXYLATE, METHOD FOR THEIR PRODUCTION AND USE THEREOF BASF SE (DE) 2007-05-03 — — WO disclosed
EP-1776010-A2 METHOD FOR PRODUCING AQUEOUS ACTIVE SUBSTANCE COMPOSITIONS OF ACTIVE SUBSTANCES THAT ARE HARDLY SOLUBLE IN WATER BASF AKTIENGESELLSCHAFT (DE) 2007-04-25 — — EP disclosed
EP-1773121-A1 LIQUID PESTICIDE COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2007-04-18 — — EP disclosed
EP-1763300-A1 USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS BASF AKTIENGESELLSCHAFT (DE) 2007-03-21 — — EP disclosed
WO-2006125647-A1 METHOD FOR DETERMINING RESIDUES IN PLASTICS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed
WO-2006125644-A1 METHOD FOR DETERMINING PESTICIDE RESIDUES IN SOIL OR PLANT MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed
WO-2006087227-A2 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF AKTIENGESELLSCHAFT (DE) 2006-08-24 — — WO disclosed
WO-2006015791-A2 METHOD FOR PRODUCING AQUEOUS ACTIVE SUBSTANCE COMPOSITIONS OF ACTIVE SUBSTANCES THAT ARE HARDLY SOLUBLE IN WATER BASF AKTIENGESELLSCHAFT (DE) 2006-02-16 — — WO disclosed
WO-2006002984-A1 LIQUID PESTICIDE COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2006-01-12 — — WO disclosed
WO-2006000592-A1 USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS BASF AKTIENGESELLSCHAFT (DE) 2006-01-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110312497-A1 USE OF HYDROPHOBIN AS A SPREADING AGENT PFN1, DSTN, CHN2 KDM1A 3749/4885SMN1; SMN2 3032/4885HRH4 288/4885
US-20110195844-A1 PROCESS FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AQUEOUS MEDIUM IDUA, PHOSPHO1, HDHD5 KDM1A 3409/4885SMN1; SMN2 3438/4885HRH4 215/4885
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER NOS1, NOS3, NPSR1 KDM1A 3481/4885SMN1; SMN2 927/4885HRH4 2937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.