Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957500 | 0.82 | ESR1 (0.33) | TSHRCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL9875235 | 0.82 | ESR1 (0.45) | TSHRCYP1A2GABRA1CYP3A4SLC6A2 | |
| SCHEMBL2542973 | 0.81 | ALDH1A1 (0.48) | TSHRCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL16960128 | 0.80 | ESR1 (0.34) | TSHRCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL12710498 | 0.79 | ADRB1 (0.33) | ALDH1A1ESR1TP53TDP1GAA | |
| SCHEMBL16960137 | 0.77 | GABRA1 (0.36) | TSHRCYP1A2GABRA1GABRG2GABRB3 | |
| SCHEMBL672658 | 0.76 | CYP2A6 (0.43) | TSHRCYP1A2CA1CA2ALDH1A1 | |
| SCHEMBL24804430 | 0.75 | ALDH1A1 (0.39) | TSHRCYP1A2GABRA1CA1CA2 | |
| SCHEMBL7594286 | 0.74 | ALDH1A1 (0.39) | TSHRGABRA1GABRB2ALDH1A1ATM | |
| SCHEMBL16959773 | 0.73 | MAPK1 (0.30) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791945-A1 | STABLE LIQUID FORMULATIONS OF PLASMID DNA | CENTELION (FR) | 2007-06-06 | — | — | EP | disclosed |
| EP-1737945-A1 | METHOD FOR PURIFYING PLASMID DNA | CENTELION (FR) | 2007-01-03 | — | — | EP | disclosed |
| WO-2006029908-A1 | STABLE LIQUID FORMULATIONS OF PLASMID DNA | CENTELION (FR) | 2006-03-23 | — | — | WO | disclosed |
| WO-2005100542-A1 | METHOD FOR PURIFYING PLASMID DNA | CENTELION (FR) | 2005-10-27 | — | — | WO | disclosed |