Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EBP | Q15125 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192506 | 0.94 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TMEM97LMNAGLA | |
| SCHEMBL5190544 | 0.87 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1SIGMAR1LMNAKMT2A | |
| SCHEMBL8589350 | 0.81 | EBP (0.57) | EBPSIGMAR1TMEM97EBPLABCB1 | |
| SCHEMBL5945465 | 0.81 | SIGMAR1 (0.37) | ALDH1A1EBPSIGMAR1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8590314 | 0.80 | EBP (0.56) | EBPSIGMAR1TMEM97EBPLABCB1 | |
| SCHEMBL5190692 | 0.79 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1LMNAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8587505 | 0.78 | EBP (0.53) | EBPSIGMAR1TMEM97EBPLABCB1 | |
| Hydrochloric Acid SCHEMBL8588944 | 0.76 | EBP (0.56) | ALDH1A1EBPSIGMAR1TMEM97EBPL | |
| SCHEMBL5191198 | 0.76 | MAPK1 (0.56) | ALDH1A1SIGMAR1ABCB1GLAKMT2A | |
| SCHEMBL5190296 | 0.76 | SIGMAR1 (0.44) | ALDH1A1L3MBTL1SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |