Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192309 | 0.83 | HTT (1.00) | HTTGAAMEN1KMT2ACYP1A2 | |
| SCHEMBL5190922 | 0.83 | HTT (0.48) | HTTGAAMAPTL3MBTL1POLB | |
| SCHEMBL123248 | 0.80 | ALDH1A1 (0.52) | HTTGAAMAPTL3MBTL1MAPK1 | |
| SCHEMBL29953885 | 0.78 | MAPT (0.50) | HTTGAAMAPTL3MBTL1MAPK1 | |
| SCHEMBL730547 | 0.78 | MAPT (0.50) | HTTGAAMAPTL3MBTL1MAPK1 | |
| SCHEMBL5190292 | 0.72 | HTT (0.78) | HTTGAAMEN1KMT2ACYP1A2 | |
| SCHEMBL15579457 | 0.70 | HTT (0.74) | HTTGAAMEN1KMT2ACYP1A2 | |
| SCHEMBL29462629 | 0.69 | PLD1 (0.68) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL230367 | 0.69 | PLD1 (0.68) | GAAMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL18228078 | 0.69 | PLD1 (0.68) | GAAMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707187-B1 | Reductive colorant for keratin fibres | WELLA AG (DE) | 2007-08-01 | — | — | EP | claimed |
| EP-1707188-B1 | Reductive colouring system for keratin fibres | WELLA AG (DE) | 2007-08-01 | — | — | EP | claimed |
| US-20060242772-A1 | Reductive colouring system for keratin fibres | THE PROCTER & GAMBLE COMPANY | 2006-11-02 | — | — | US | claimed |
| US-20060230548-A1 | Reductive colorant for keratin fibres | THE PROCTER & GAMBLE COMPANY | 2006-10-19 | — | — | US | claimed |
| EP-1707188-A1 | Reductive colouring system for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | claimed |
| EP-1707187-B1 | Reductive colorant for keratin fibres | WELLA AG (DE) | 2007-08-01 | — | — | EP | disclosed |
| US-20060230548-A1 | Reductive colorant for keratin fibres | THE PROCTER & GAMBLE COMPANY | 2006-10-19 | — | — | US | disclosed |
| WO-2006107595-A1 | REDUCTIVE COLORANT FOR KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-10-12 | — | — | WO | disclosed |
| EP-1707187-A1 | Reductive colorant for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060242772-A1 | Reductive colouring system for keratin fibres | KRT18, OAT, COX6C | HTT 3641/4885GAA 4521/4885MEN1 4025/4885 |
| US-20060230548-A1 | Reductive colorant for keratin fibres | KRT18, COX6C, CYC1 | HTT 2961/4885GAA 4674/4885MEN1 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.