Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190292 | 0.87 | HTT (0.78) | HTTGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL15579457 | 0.85 | HTT (0.74) | HTTGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL5190253 | 0.83 | HTT (0.71) | HTTGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL16923162 | 0.83 | HTT (0.70) | HTTGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL5191835 | 0.79 | HTT (0.65) | HTTGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL15579067 | 0.78 | HTT (0.63) | HTTGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL3835167 | 0.78 | HTT (0.64) | HTTGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL1779819 | 0.78 | HTT (0.64) | HTTGAAKMT2AMEN1MAPT | |
| SCHEMBL5928922 | 0.77 | LMNA (0.70) | HTTGAAKMT2AMEN1CYP1A2 | |
| SCHEMBL11487535 | 0.76 | LMNA (0.74) | HTTGAAKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707187-B1 | Reductive colorant for keratin fibres | WELLA AG (DE) | 2007-08-01 | — | — | EP | claimed |
| EP-1707188-B1 | Reductive colouring system for keratin fibres | WELLA AG (DE) | 2007-08-01 | — | — | EP | claimed |
| US-20060242772-A1 | Reductive colouring system for keratin fibres | THE PROCTER & GAMBLE COMPANY | 2006-11-02 | — | — | US | claimed |
| US-20060230548-A1 | Reductive colorant for keratin fibres | THE PROCTER & GAMBLE COMPANY | 2006-10-19 | — | — | US | claimed |
| WO-2006107595-A1 | REDUCTIVE COLORANT FOR KERATIN FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2006-10-12 | — | — | WO | claimed |
| EP-1707187-A1 | Reductive colorant for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | claimed |
| EP-1707188-A1 | Reductive colouring system for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | claimed |
| EP-1707187-B1 | Reductive colorant for keratin fibres | WELLA AG (DE) | 2007-08-01 | — | — | EP | disclosed |
| US-20060230548-A1 | Reductive colorant for keratin fibres | THE PROCTER & GAMBLE COMPANY | 2006-10-19 | — | — | US | disclosed |
| EP-1707187-A1 | Reductive colorant for keratin fibres | Wella Aktiengesellschaft (DE) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060242772-A1 | Reductive colouring system for keratin fibres | KRT18, OAT, COX6C | HTT 3641/4885GAA 4521/4885KMT2A 1398/4885 |
| US-20060230548-A1 | Reductive colorant for keratin fibres | KRT18, COX6C, CYC1 | HTT 2961/4885GAA 4674/4885KMT2A 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.