Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CDA | P32320 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15055105 | 0.86 | MAPT (0.40) | PDE4DPDE3ASLC29A1LMNAMTOR | |
| SCHEMBL29891526 | 0.83 | LMNA (0.36) | PDE4DPDE3ASLC29A1LMNAMTOR | |
| SCHEMBL223208 | 0.83 | PDE3A (0.54) | PDE4DPDE3ASLC29A1LMNAMTOR | |
| Hydrochloric Acid SCHEMBL28104164 | 0.82 | PDE3A (0.53) | PDE4DPDE3ASLC29A1LMNAMTOR | |
| SCHEMBL29891333 | 0.81 | LMNA (0.34) | PDE4DPDE3ASLC29A1LMNAMTOR | |
| SCHEMBL29413003 | 0.80 | LMNA (0.33) | PDE4DPDE3ASLC29A1LMNAMTOR | |
| SCHEMBL4201672 | 0.78 | LMNA (0.43) | LMNAMAPTP2RY6POLBSMN1; SMN2 | |
| SCHEMBL30919320 | 0.76 | ADORA3 (0.35) | P2RY6POLBP2RY2P2RY4 | |
| SCHEMBL23258348 | 0.75 | PDE3A (0.56) | PDE4DPDE3ASLC29A1LMNAMTOR | |
| SCHEMBL5192208 | 0.74 | P2RY6 (0.33) | PDE4DPDE3ASLC29A1LMNAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812456-A2 | ß-L-N4-HYDROXYCYTOSINE DEOXYNUCLEOSIDES AND THEIR USE AS PHARMACEUTICAL AGENTS IN THE PROPHYLAXIS OR THERAPY OF VIRAL DISEASES | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006045616-A2 | β-L-N4-HYDROXYCYTOSINE DEOXYNUCLEOSIDES AND THEIR USE AS PHARMACEUTICAL AGENTS IN THE PROPHYLAXIS OR THERAPY OF VIRAL DISEASES | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2006-05-04 | — | — | WO | disclosed |