Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23753955 | 0.88 | PDE4A (0.58) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7440781 | 0.79 | PDE4B (0.57) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7733862 | 0.78 | PDE4B (0.60) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7328799 | 0.77 | PDE4B (0.57) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7447179 | 0.76 | PDE4B (0.74) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7447175 | 0.76 | PDE4B (0.74) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7301103 | 0.76 | KDM4E (0.69) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL7301099 | 0.76 | KDM4E (0.69) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL30025682 | 0.76 | KDM4E (0.69) | PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL8862741 | 0.76 | PDE4A (0.51) | PDE4APDE4BPDE4DPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799634-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006026747-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |