Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MPO | P05164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TPO | P07202 | 1/20 | 0.39 |
| ▸ | EPX | P11678 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28152070 | 0.79 | ADCY10 (0.45) | RAB9ANPC1SMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL5191147 | 0.77 | MPO (0.43) | RAB9ANPC1SMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL3602925 | 0.70 | HSP90AA1 (0.51) | RAB9ANPC1SMN1; SMN2POLBMEN1 | |
| SCHEMBL8379832 | 0.70 | ADORA2A (0.50) | RAB9ANPC1SMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL27787219 | 0.70 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2POLBCYP3A4 | |
| SCHEMBL3526925 | 0.70 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL28151082 | 0.67 | ADORA2A (0.52) | RAB9ANPC1SMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL10882423 | 0.66 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2POLBCYP3A4 | |
| SCHEMBL21223129 | 0.64 | HTR2A (0.41) | RAB9ANPC1SMN1; SMN2ADORA1MPO | |
| SCHEMBL6229874 | 0.64 | CALM1 (0.58) | SMN1; SMN2CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796673-A2 | NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Reddy US Therapeutics, Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006034473-A2 | NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS, INC. (US) | 2006-03-30 | — | — | WO | disclosed |