Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199484 | 0.81 | MAPT (0.51) | MAPTSMN1; SMN2KMT2ABLMTSHR | |
| SCHEMBL5193973 | 0.80 | MAPT (0.47) | MAPTSMN1; SMN2KMT2ABLMMEN1 | |
| SCHEMBL5190772 | 0.77 | OGA (0.46) | MAPTSMN1; SMN2KMT2ABLMTSHR | |
| SCHEMBL5193442 | 0.77 | MAPT (0.55) | MAPTSMN1; SMN2KMT2ACA12CA1 | |
| SCHEMBL5190603 | 0.73 | FFAR1 (0.42) | SMN1; SMN2KMT2ATSHRMEN1POLB | |
| SCHEMBL5194086 | 0.72 | FAAH (0.62) | MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5193199 | 0.71 | MAPT (0.55) | MAPTSMN1; SMN2KMT2ABLMTSHR | |
| SCHEMBL5210351 | 0.70 | FAAH (0.46) | MAPTKMT2AMEN1CCR2LMNA | |
| SCHEMBL28869329 | 0.69 | MAPT (1.00) | MAPTSMN1; SMN2KMT2ACA12CA1 | |
| SCHEMBL5193490 | 0.69 | FAAH (0.50) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |