Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | EBP | Q15125 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5194021 | 0.86 | SIGMAR1 (0.54) | DRD4SIGMAR1 | |
| SCHEMBL5378298 | 0.79 | DRD4 (0.47) | DRD4SIGMAR1MEN1KMT2APOLB | |
| SCHEMBL5196325 | 0.76 | DRD4 (0.64) | DRD4SMN1; SMN2 | |
| SCHEMBL8828288 | 0.75 | SIGMAR1 (0.54) | SIGMAR1EBPTMEM97DHCR7 | |
| SCHEMBL3552685 | 0.75 | SIGMAR1 (0.49) | SIGMAR1EBPTMEM97CHRM3ALDH1A1 | |
| SCHEMBL3560527 | 0.75 | SIGMAR1 (0.49) | SIGMAR1EBPTMEM97CHRM3ALDH1A1 | |
| SCHEMBL10511464 | 0.74 | EBP (0.56) | SIGMAR1EBPTMEM97DHCR7LMNA | |
| SCHEMBL27334030 | 0.74 | SIGMAR1 (0.56) | SIGMAR1EBPTMEM97CHRM3MEN1 | |
| SCHEMBL9739025 | 0.73 | HTR1A (0.56) | SIGMAR1EBPTMEM97DHCR7 | |
| SCHEMBL7351513 | 0.73 | SIGMAR1 (0.53) | SIGMAR1EBPTMEM97CHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |