Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.70 |
| ▸ | ACHE | P22303 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190111 | 0.90 | PRKCI (0.74) | PRKCIACHEPOLBALDH1A1MAPK1 | |
| SCHEMBL5190941 | 0.83 | PRKCI (0.54) | PRKCIACHEPOLBALDH1A1KDM4E | |
| SCHEMBL20869672 | 0.83 | PRKCI (0.50) | PRKCIACHEALDH1A1MAPK1MAPT | |
| SCHEMBL29565648 | 0.83 | PRKCI (1.00) | PRKCIACHEPOLBALDH1A1MAPK1 | |
| SCHEMBL111109 | 0.83 | PRKCI (1.00) | PRKCIACHEPOLBALDH1A1MAPK1 | |
| SCHEMBL309824 | 0.81 | PRKCI (0.59) | PRKCIACHEMAPK1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL1998656 | 0.81 | ACHE (1.00) | PRKCIACHEPOLBALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL1998660 | 0.81 | ACHE (1.00) | PRKCIACHEPOLBALDH1A1MAPK1 | |
| SCHEMBL6175929 | 0.81 | PRKCI (0.47) | PRKCIACHEKDM4EMAPTMPO | |
| SCHEMBL3579492 | 0.80 | PRKCI (0.58) | PRKCIACHEALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361851-B1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2007-02-21 | — | — | EP | disclosed |
| US-7070630-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-04 | — | — | US | disclosed |
| EP-1361851-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040211011-A1 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-10-28 | — | — | US | disclosed |
| US-6750339-B2 | SUCH AS 4-AMINO-2-(2-DIMETHYLAMINO-ETHYL)-PHENOL; USEFUL IN PLACE OF P-AMINOPHENOL | THE PROCTER AND GAMBLE COMPANY | 2004-06-15 | — | — | US | disclosed |
| EP-1361851-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G-Clairol, Inc. (US) | 2003-11-19 | — | — | EP | disclosed |
| US-20020148052-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-17 | — | — | US | disclosed |
| WO-2002058653-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020148052-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-ND1 | PRKCI 3484/4885ACHE 4672/4885POLB 351/4885 |
| US-20040211011-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-ND1 | PRKCI 3484/4885ACHE 4672/4885POLB 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.