Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190941 | 0.89 | PRKCI (0.54) | PRKCIACHEHTR7HTR2AHTR2C | |
| SCHEMBL9759946 | 0.85 | HTR2A (0.45) | PRKCIACHEHTR7HTR2AHTR2C | |
| SCHEMBL3338265 | 0.82 | PRKCI (0.69) | PRKCIACHEHTR2APDE10AKDM4E | |
| SCHEMBL29834174 | 0.82 | PRKCI (0.69) | PRKCIACHEHTR2APDE10AKDM4E | |
| SCHEMBL21214846 | 0.82 | PRKCI (0.59) | PRKCIACHEHTR2APDE10AKDM4E | |
| SCHEMBL5190111 | 0.82 | PRKCI (0.74) | PRKCIACHEHTR2CPDE10AHTR1A | |
| SCHEMBL12006085 | 0.81 | TAAR1 (0.41) | PRKCIACHEHTR2AHTR2CHTR2B | |
| SCHEMBL10949866 | 0.79 | AMY1A (0.52) | HTR7HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL5983338 | 0.79 | HRH3 (0.50) | HTR7HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL5381058 | 0.79 | PRKCI (0.63) | PRKCIACHEPDE10AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361851-B1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2007-02-21 | — | — | EP | disclosed |
| CN-1264498-C | Primary intermediates for oxidative dyeing of hair | PROCTER & GAMBLE (US) | 2006-07-19 | — | — | CN | disclosed |
| US-7070630-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-04 | — | — | US | disclosed |
| CN-1607935-A | Primary intermediates for oxidative dyeing of hair | PROCTER & GAMBLE (US) | 2005-04-20 | — | — | CN | disclosed |
| EP-1361851-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040211011-A1 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-10-28 | — | — | US | disclosed |
| US-6750339-B2 | SUCH AS 4-AMINO-2-(2-DIMETHYLAMINO-ETHYL)-PHENOL; USEFUL IN PLACE OF P-AMINOPHENOL | THE PROCTER AND GAMBLE COMPANY | 2004-06-15 | — | — | US | disclosed |
| EP-1361851-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G-Clairol, Inc. (US) | 2003-11-19 | — | — | EP | disclosed |
| US-20020148052-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-17 | — | — | US | disclosed |
| WO-2002058653-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020148052-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-ND1 | PRKCI 3484/4885ACHE 4672/4885HTR7 2412/4885 |
| US-20040211011-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-ND1 | PRKCI 3484/4885ACHE 4672/4885HTR7 2412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.