SCHEMBL5192971

SCHEMBL5192971

CCCc1ccc(OC(=O)O)c(O)c1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.49
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
MCL1 Q07820 1/20 0.45
PPARA Q07869 1/20 0.45
IAPP P10997 1/20 0.45
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45
APEX1 P27695 1/20 0.45
KMT2A Q03164 1/20 0.45
CYP19A1 P11511 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5194907 0.90 PPARA (0.54) PPARA
SCHEMBL5675084 0.89 PPARA (0.60) PPARA
SCHEMBL5681042 0.86 TRPA1 (0.52) GAA
SCHEMBL4372737 0.81 PTPN1 (0.40) CNR1CNR2CYP3A4MCL1PPARA
SCHEMBL16315989 0.79 CNR1 (0.52) CNR1CNR2CYP1A2CYP3A4TSHR
SCHEMBL901444 0.79 CYP3A4 (0.71) GAACNR1CNR2CYP1A2CYP3A4
SCHEMBL29833121 0.79 CYP3A4 (0.71) GAACNR1CNR2CYP1A2CYP3A4
SCHEMBL238573 0.78 GABRA1 (0.44) CNR1CNR2
SCHEMBL5676633 0.78 KAT8 (0.54) CYP1A2CYP3A4PPARAIAPP
SCHEMBL532205 0.77 CNR1 (0.53) GAACNR1CNR2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019053541-A1 ACRYLATES THROUGH OLEFIN/CARBON DIOXIDE COUPLING SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-03-21 WO disclosed
WO-2019053540-A1 METHODS OF PRODUCING ALPHA, BETA-UNSATURATED CARBOXYLIC ACID SALTS FROM ALKANES AND CARBON DIOXIDE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-03-21 WO disclosed
WO-2017158469-A1 METHODS OF MAKING ALPHA, BETA-UNSATURATED CARBOXYLIC ACIDS OR SALTS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-09-21 WO disclosed
EP-1620447-B1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III EXXONMOBIL CHEM PATENTS INC (US) 2007-08-08 EP disclosed
US-20060036049-A1 Soluble late transition metal catalysts for olefin oligomerizations III ZHAO BAIYI 2006-02-16 US disclosed
EP-1620447-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III Exxonmobil Chemical Patents Inc. (US) 2006-02-01 EP disclosed
WO-2003102006-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-12-11 WO disclosed
US-5681669-A ORGANIC SOLVENT CONTAINING AN AROMATIC CARBONATE AND DISSOLVED LITHIUM SALT UBE INDUSTRIES, LTD. (JP) 1997-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060036049-A1 Soluble late transition metal catalysts for olefin oligomerizations III COMT, CD69, SPR GAA 1647/4885CNR1 3890/4885CNR2 4148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.