Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5191281 | 0.81 | BRPF1 (0.47) | BRPF1PARP1BRD4CREBBPHSD17B10 | |
| SCHEMBL5194276 | 0.78 | LMNA (0.46) | BRPF1BRD4CREBBPHSD17B10HSD17B3 | |
| SCHEMBL5196715 | 0.78 | BRPF1 (0.41) | BRPF1BRD4CREBBPHSD17B10HSD17B3 | |
| SCHEMBL5193610 | 0.78 | BRPF1 (0.44) | BRPF1PARP1BRD4CREBBPHSD17B10 | |
| SCHEMBL5193417 | 0.78 | GSK3A (0.51) | BRPF1PARP1BRD4ALDH1A1ACHE | |
| SCHEMBL5191836 | 0.77 | ITGB3 (0.52) | BRPF1BRD4CREBBPHSD17B10HSD17B3 | |
| SCHEMBL5193966 | 0.75 | ACHE (0.47) | BRPF1PARP1BRD4CREBBPHSD17B10 | |
| SCHEMBL14374090 | 0.75 | KDM4E (0.41) | BRPF1BRD4CREBBPHSD17B3ALOX15 | |
| SCHEMBL5193362 | 0.74 | BRD4 (0.61) | BRPF1BRD4CREBBPHSD17B10HSD17B3 | |
| SCHEMBL5194517 | 0.74 | KDM4E (0.56) | BRPF1BRD4CREBBPHSD17B10HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1813603-A1 | AROMATIC AMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICAL USES OF BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
| EP-1813603-A1 | AROMATIC AMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICAL USES OF BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | AVPR2, AVPR1A, AVPR1B | BRPF1 4136/4885PARP1 4198/4885BRD4 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.