Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192491 | 0.91 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5194854 | 0.81 | NPC1 (0.44) | ALDH1A1POLBHPGD | |
| SCHEMBL5190018 | 0.79 | PKM (0.49) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL5195352 | 0.76 | ALDH1A1 (0.58) | ALDH1A1PTPN1POLBMAPTKDM4E | |
| SCHEMBL5192443 | 0.76 | ALDH1A1 (0.48) | ALDH1A1POLBKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5193432 | 0.76 | MAPT (0.50) | MAPTSMN1; SMN2 | |
| SCHEMBL5193308 | 0.76 | POLB (0.47) | ALDH1A1POLBMAPTKDM4EHSD17B10 | |
| SCHEMBL5193468 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL5190765 | 0.76 | CHRM1 (0.47) | ALDH1A1POLBMAPTKDM4EHSD17B10 | |
| SCHEMBL5190775 | 0.75 | MAPT (0.49) | ALDH1A1POLBMAPTHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |