SCHEMBL519563

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3849213	0.89	CYP3A4 (0.36)	KDM4EMEN1KMT2AALDH1A1MAPT
	SCHEMBL3846787	0.89	POLB (0.39)	KDM4EMEN1KMT2AALDH1A1MAPT
	SCHEMBL3848485	0.89	MEN1 (0.42)	KDM4EMEN1KMT2AALDH1A1USP2
	SCHEMBL3846098	0.89	GAA (0.39)	KDM4EMEN1KMT2AL3MBTL1AURKA
	SCHEMBL3852882	0.88	KIF11 (0.43)	KDM4EMEN1KMT2AALDH1A1MAPT
	SCHEMBL3845601	0.85	ALDH1A1 (0.39)	KDM4EMEN1KMT2AALDH1A1L3MBTL1
	SCHEMBL3846485	0.85	RAB9A (0.45)	KDM4EMEN1KMT2AALDH1A1L3MBTL1
	SCHEMBL3850096	0.85	PTGS2 (0.39)	MEN1KMT2AALDH1A1PTGS2NPC1
	SCHEMBL4717109	0.84	MAP2K4 (0.42)	MEN1KMT2AMAPTMAPK1HPGD
	SCHEMBL3845929	0.83	PTGS2 (0.36)	KDM4EALDH1A1MAPTPTGS2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.