Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.74 |
| ▸ | DRD2 | P14416 | 8/20 | 0.74 |
| ▸ | DRD3 | P35462 | 8/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | HTR7 | P34969 | 1/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14281102 | 0.86 | DRD4 (0.80) | DRD4DRD2DRD3L3MBTL1HTR7 | |
| SCHEMBL5198967 | 0.84 | DRD4 (0.80) | DRD4DRD2DRD3L3MBTL1BCHE | |
| SCHEMBL18499093 | 0.84 | L3MBTL1 (1.00) | DRD4DRD2DRD3L3MBTL1HTR7 | |
| SCHEMBL5198113 | 0.84 | DRD2 (0.80) | DRD4DRD2DRD3L3MBTL1BCHE | |
| SCHEMBL5198717 | 0.84 | DRD2 (1.00) | DRD4DRD2DRD3L3MBTL1HTR7 | |
| SCHEMBL5199201 | 0.81 | HTR7 (1.00) | DRD4DRD2DRD3HTR7CYP2D6 | |
| SCHEMBL23964192 | 0.81 | DRD4 (0.80) | DRD4DRD2DRD3L3MBTL1BCHE | |
| SCHEMBL5196816 | 0.81 | DRD2 (0.71) | DRD4DRD2DRD3L3MBTL1HTR7 | |
| SCHEMBL5198132 | 0.81 | LMNA (0.72) | DRD4DRD2DRD3L3MBTL1HTR7 | |
| SCHEMBL5198662 | 0.78 | DRD4 (0.67) | DRD4DRD2DRD3L3MBTL1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815866-A1 | REMEDY OR PREVENTIVE FOR ISCHEMIC CARDIAC DISEASE OR ISCHEMIC CARDIAC MYOPATHY | Neugen Pharma, Inc (JP) | 2007-08-08 | — | — | EP | disclosed |