Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 6/20 | 0.57 |
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | DRD3 | P35462 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197670 | 0.85 | HTR2A (0.76) | LMNAPOLBTSHRCYP2D6DRD4 | |
| SCHEMBL8797561 | 0.81 | KMT2A (0.56) | LMNAHTTTSHRDRD4L3MBTL1 | |
| SCHEMBL5199448 | 0.81 | DRD2 (0.55) | LMNAHTTPOLBTSHRBCHE | |
| SCHEMBL5196668 | 0.81 | DRD2 (0.56) | LMNAHTTPOLBTSHRBCHE | |
| Hydrochloric Acid SCHEMBL9393795 | 0.80 | KMT2A (0.55) | LMNAHTTTSHRDRD4L3MBTL1 | |
| SCHEMBL946337 | 0.80 | LMNA (0.77) | LMNAHTTPOLBTSHRBCHE | |
| SCHEMBL2131581 | 0.79 | HCRTR2 (0.70) | — | |
| SCHEMBL3612541 | 0.77 | DGAT1 (0.52) | LMNAPOLBDRD4DRD2DRD3 | |
| SCHEMBL2268646 | 0.76 | AR (0.63) | LMNAHTTPOLBTSHRBCHE | |
| SCHEMBL12783901 | 0.75 | BCHE (0.73) | LMNAHTTPOLBTSHRBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815866-A1 | REMEDY OR PREVENTIVE FOR ISCHEMIC CARDIAC DISEASE OR ISCHEMIC CARDIAC MYOPATHY | Neugen Pharma, Inc (JP) | 2007-08-08 | — | — | EP | disclosed |