Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.55 |
| ▸ | DRD4 | P21917 | 5/20 | 0.55 |
| ▸ | DRD3 | P35462 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197306 | 0.86 | HTR2A (0.67) | DRD2DRD4DRD3LMNAGRM2 | |
| SCHEMBL5196369 | 0.81 | LMNA (0.60) | DRD2DRD4DRD3LMNAHTT | |
| SCHEMBL5196668 | 0.80 | DRD2 (0.56) | DRD2DRD4DRD3LMNAHTT | |
| SCHEMBL4244132 | 0.79 | MEN1 (0.56) | DRD2DRD4DRD3LMNAHTT | |
| SCHEMBL4251327 | 0.74 | SMN1; SMN2 (0.62) | DRD2DRD4DRD3LMNAHTT | |
| SCHEMBL8328575 | 0.74 | DRD4 (0.68) | DRD2DRD4DRD3LMNATSHR | |
| SCHEMBL946337 | 0.72 | LMNA (0.77) | DRD2DRD4DRD3LMNAHTT | |
| SCHEMBL4254154 | 0.72 | SMN1; SMN2 (0.51) | DRD2DRD4DRD3LMNAHTT | |
| SCHEMBL12783901 | 0.72 | BCHE (0.73) | DRD2DRD4DRD3LMNAHTT | |
| SCHEMBL24606221 | 0.71 | GRM2 (1.00) | DRD2DRD4DRD3LMNAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815866-A1 | REMEDY OR PREVENTIVE FOR ISCHEMIC CARDIAC DISEASE OR ISCHEMIC CARDIAC MYOPATHY | Neugen Pharma, Inc (JP) | 2007-08-08 | — | — | EP | disclosed |