Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15670481 | 0.76 | KCNN4 (0.40) | HDAC1HDAC2 | |
| SCHEMBL5778950 | 0.74 | ADRA1A (0.38) | ALDH1A1MAPTKMT2ATDP1PKM | |
| SCHEMBL5194744 | 0.72 | GRM2 (0.38) | HDAC1HDAC2ALDH1A1MAPTMEN1 | |
| SCHEMBL188322 | 0.69 | MAPT (0.46) | HDAC1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28779611 | 0.68 | HDAC1 (0.40) | HDAC1HDAC2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5191753 | 0.67 | MAPT (0.38) | HDAC1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2891442 | 0.67 | DGAT1 (0.37) | LMNA | |
| SCHEMBL2898661 | 0.67 | DGAT1 (0.37) | LMNA | |
| SCHEMBL16887793 | 0.67 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL9744548 | 0.67 | CLCN2 (0.46) | ALDH1A1MAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1813603-A1 | AROMATIC AMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICAL USES OF BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | AVPR2, AVPR1A, AVPR1B | HDAC1 1198/4885HDAC2 1104/4885ALDH1A1 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.