Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 8/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5196152 | 0.98 | MAPK8 (0.38) | MAPK8MAPK10PTK2ABCC1MAPK9 | |
| SCHEMBL12451748 | 0.75 | KMT2A (0.46) | MAPK8MAPK10MAPK9LMNAKMT2A | |
| SCHEMBL5198536 | 0.74 | MAPK8 (0.32) | MAPK8MAPK10MAPK9HTTLMNA | |
| SCHEMBL4574859 | 0.73 | ALDH1A1 (0.41) | MAPK8HTTALOX5KMT2ANPC1 | |
| SCHEMBL28981221 | 0.73 | ALOX5 (0.35) | MAPK8MAPK10PTK2HTTALOX5 | |
| Hydrochloric Acid SCHEMBL3623037 | 0.69 | ALOX5 (0.36) | MAPK8MAPK10HTTALOX5LMNA | |
| SCHEMBL3580345 | 0.67 | PTPN2 (0.61) | MAPK8MAPK10ABCC1LMNAHPGD | |
| SCHEMBL28271002 | 0.67 | PTK2 (0.42) | MAPK8MAPK10PTK2ABCC1HTT | |
| SCHEMBL23616663 | 0.66 | KMT2A (0.38) | MAPK8MAPK10ABCC1MAPK9HTT | |
| SCHEMBL28311905 | 0.66 | ALOX5 (0.30) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868983-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 1-SUBSTITUTED-3-AMINOALCOHOLS | LONZA AG (CH) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006087166-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 1-SUBSTITUTED-3-AMINOALCOHOLS | LONZA AG (CH) | 2006-08-24 | — | — | WO | disclosed |