SCHEMBL5196671

SCHEMBL5196671

F[B-](F)(F)F.N#[N+]c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
HSD17B10 Q99714 5/20 0.52
ALOX12 P18054 4/20 0.52
L3MBTL1 Q9Y468 4/20 0.52
TSHR P16473 4/20 0.52
TDP1 Q9NUW8 4/20 0.52
ALOX15 P16050 2/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52
MAPK1 P28482 1/20 0.52
PTGS2 P35354 1/20 0.52
HTR2B P41595 1/20 0.52
CYP3A4 P08684 5/20 0.43
MAPT P10636 5/20 0.43
HPGD P15428 3/20 0.43
HTT P42858 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
MEN1 O00255 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL741543 0.92 ALDH1A1 (0.62) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL11034190 0.92 L3MBTL1 (0.36) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
Bromide SCHEMBL8910214 0.90 ALDH1A1 (0.59) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
Hydrochloric Acid SCHEMBL8911949 0.90 ALDH1A1 (0.59) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
Hydrochloric Acid SCHEMBL11570682 0.88 ALDH1A1 (0.56) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
Hydrochloric Acid SCHEMBL10936047 0.88 ALDH1A1 (0.56) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
Formaldehyde SCHEMBL8778614 0.86 ALDH1A1 (0.54) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
SCHEMBL9854058 0.82 ALDH1A1 (0.45) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
Sulfuric Acid SCHEMBL5718122 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR
Sulfuric Acid SCHEMBL2959599 0.81 ALDH1A1 (0.48) ALDH1A1HSD17B10ALOX12L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1554117-B1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2007-08-08 EP disclosed
US-7198877-B2 Heat-sensitive lithographic printing plate precursor AGFA-GEVAERT (BE) 2007-04-03 US disclosed
US-20060019190-A1 Heat-sensitive lithographic printing plate precursor AGFA-GEVAERT (BE) 2006-01-26 US disclosed
EP-1554117-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR Agfa-Gevaert (BE) 2005-07-20 EP disclosed
WO-2004035310-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA-GEVAERT (BE) 2004-04-29 WO disclosed
US-6136425-A SUITABLE FOR A PRINTING PLATE WHICH GIVES AN EXCELLENT WATER RETENTION PROPERTY AND PREVENTS STAINS FROM OCCURRING AT NON-IMAGE PORTIONS KONICA CORPORATION (JP) 2000-10-24 US disclosed
US-5380622-A Phenol-formaldehyde-naphthoquinone diazide BASF AKTIENGESELLSCHAFT (DE) 1995-01-10 US disclosed
EP-0453950-A2 Process for the production of negative relief images BASF Aktiengesellschaft (DE) 1991-10-30 EP disclosed
US-4578341-A Acidic photosensitive relief image-forming materials with indicator pigment or dye SENSITISERS (RESEARCH) LTD. (GB) 1986-03-25 US disclosed
EP-0041984-B1 DIAZONIUM IMAGING SYSTEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-09-19 EP disclosed
US-4394433-A Diazonium imaging system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-07-19 US disclosed
EP-0061319-A1 Photosensitive relief image-forming materials and method of forming relief images using same Sensitisers (Research) Limited (GB) 1982-09-29 EP disclosed
EP-0041984-A4 DIAZONIUM IMAGING SYSTEM. MINNESOTA MINING & MFG (US) 1982-05-10 EP disclosed
EP-0041984-A1 DIAZONIUM IMAGING SYSTEM. MINNESOTA MINING & MFG (US) 1981-12-23 EP disclosed
US-4296194-A O-QUINONE DIAZIDE AND/OR DIAZONIUM COMPOUND, DECOMPOSITION, REACTION WITH AZO DYE TO PRODUCE DIFFERENT COLOR VICKERS LIMITED (GB) 1981-10-20 US disclosed
WO-1981001756-A1 DIAZONIUM IMAGING SYSTEM MINNESOTA MINING & MFG (US) 1981-06-25 WO disclosed
US-4252592-A Method of making epoxide resin-impregnated composites CIBA-GEIGY CORPORATION (US) 1981-02-24 US disclosed
US-4218279-A Bonding method employing film adhesives containing an epoxide resin CIBA-GEIGY CORPORATION (US) 1980-08-19 US disclosed
US-4172772-A ELECTROLYTICALLY GRAINING ALUMINUM OR ALUMINUM ALLOY PLATES VICKERS LIMITED (GB) 1979-10-30 US disclosed