Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 2/20 | 0.39 |
| ▸ | MC5R | P33032 | 2/20 | 0.39 |
| ▸ | MC3R | P41968 | 2/20 | 0.39 |
| ▸ | MC1R | Q01726 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5370825 | 0.89 | MC4R (0.40) | MEN1KMT2AHTTALDH1A1MC4R | |
| SCHEMBL5444005 | 0.88 | MC4R (0.42) | MC4RMC5RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL5458137 | 0.87 | MC4R (0.42) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5449611 | 0.86 | GPR119 (0.42) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL5449383 | 0.85 | MEN1 (0.44) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL5199301 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL5449365 | 0.84 | MC4R (0.42) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL5451925 | 0.80 | EPHX1 (0.49) | MEN1KMT2AGPR119ALDH1A1EPHX1 | |
| SCHEMBL655029 | 0.79 | YAP1 (0.54) | MEN1KMT2AHTTSMN1; SMN2NPSR1 | |
| SCHEMBL3147740 | 0.79 | YAP1 (0.54) | MEN1KMT2AHTTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-08-16 | — | — | US | disclosed |
| EP-1786809-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | Sanofi-Aventis (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021656-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | MC4R, MC5R, TAAR5 | MEN1 1307/4885KMT2A 1421/4885HTT 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.