Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450791 | 0.84 | GPR119 (0.60) | EPHX2ALDH1A1BACE1 | |
| SCHEMBL24538180 | 0.81 | TRPM8 (0.47) | TRPM8EPHX2MAPT | |
| SCHEMBL5195017 | 0.80 | CYP51A1 (0.45) | CHRM2CHRM3GAAOPRM1HRH3 | |
| SCHEMBL5444808 | 0.75 | TDP1 (0.45) | TRPM8SMN1; SMN2ALDH1A1 | |
| SCHEMBL2636579 | 0.73 | HSD11B1 (0.61) | GAAHPGDMAPTSMN1; SMN2POLB | |
| SCHEMBL16989405 | 0.72 | GPR119 (0.73) | — | |
| SCHEMBL31023784 | 0.72 | SMN1; SMN2 (0.48) | TRPM8MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL25174711 | 0.71 | HSD11B1 (0.70) | GAAHPGDMAPTSMN1; SMN2HSD11B1 | |
| SCHEMBL2606351 | 0.71 | HPGD (0.58) | GAAEPHX2HPGDSMN1; SMN2POLB | |
| SCHEMBL4962237 | 0.71 | POLB (0.78) | GAASMN1; SMN2POLBHSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786809-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | Sanofi-Aventis (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021656-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | disclosed |