SCHEMBL9824149

SCHEMBL9824149

CCN(CC)Cc1c(C)nc2ncnn2c1O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
ENPP1 P22413 9/20 0.44
MAPK1 P28482 2/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
USP2 O75604 1/20 0.42
MAPT P10636 1/20 0.41
HTT P42858 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5197330 0.83 MEN1 (0.55) HSD17B10L3MBTL1ENPP1MAPK1LMNA
SCHEMBL9770335 0.82 HSD17B10 (0.56) HSD17B10L3MBTL1ENPP1MAPK1MEN1
SCHEMBL7553783 0.80 LMNA (0.43) HSD17B10L3MBTL1ENPP1MAPK1LMNA
SCHEMBL10493808 0.78 HSD17B10 (0.50) HSD17B10L3MBTL1ENPP1MAPK1LMNA
SCHEMBL12769185 0.78 HSD17B10 (0.52) HSD17B10L3MBTL1ENPP1MAPK1MEN1
SCHEMBL10493810 0.77 HSD17B10 (0.49) HSD17B10L3MBTL1ENPP1MAPK1LMNA
SCHEMBL9770175 0.77 HSD17B10 (0.49) HSD17B10L3MBTL1ENPP1MAPK1LMNA
SCHEMBL13140138 0.75 HSD17B10 (0.60) HSD17B10L3MBTL1ENPP1MAPK1USP2
SCHEMBL5199168 0.73 TSHR (0.50) HSD17B10L3MBTL1ENPP1MAPK1LMNA
SCHEMBL24128962 0.71 ENPP1 (0.53) ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208346-B1 DIFFUSION TRANSFER REVERSAL PROCESS AGFA-GEVAERT N.V. (BE) 1991-11-21 EP disclosed
US-4859565-A Diffusion transfer reversal process AGFA-GEVAERT, N.V. (BE) 1989-08-22 US disclosed
EP-0190375-B1 SUBSTITUTED TRIAZOLOPYRIMIDINES AND THEIR USE IN LIGHT-SENSITIVE PHOTOGRAPHIC ELEMENTS AGFA-GEVAERT N.V. (BE) 1989-04-19 EP disclosed
US-4727017-A ANTIFOGGING AGENTS; STABILIZERS AGFA-GEVAERT, N.V. (BE) 1988-02-23 US disclosed
EP-0208346-A2 Diffusion transfer reversal process AGFA-GEVAERT N.V. (BE) 1987-01-14 EP disclosed