SCHEMBL5199168

SCHEMBL5199168

Cc1nc2ncnn2c(O)c1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
ALDH1A1 P00352 5/20 0.47
HSD17B10 Q99714 3/20 0.45
PAX2 Q02962 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPK1 P28482 3/20 0.43
USP2 O75604 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
LMNA P02545 2/20 0.43
TP53 P04637 1/20 0.43
ALOX15 P16050 1/20 0.43
ENPP1 P22413 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HTT P42858 2/20 0.41
CYP1A2 P05177 2/20 0.41
NPC1 O15118 1/20 0.41
GALR3 O60755 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457105 0.81 ALDH1A1 (0.44) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9824226 0.81 ALDH1A1 (0.44) TSHRALDH1A1HSD17B10USP2ENPP1
SCHEMBL7597284 0.80 ALDH1A1 (0.43) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9770335 0.80 HSD17B10 (0.56) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL353089 0.80 HSD17B10 (0.55) TSHRALDH1A1HSD17B10PAX2MEN1
SCHEMBL5197330 0.79 MEN1 (0.55) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL19193508 0.79 ALDH1A1 (0.42) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL5672150 0.78 TSHR (0.41) TSHRALDH1A1HSD17B10MAPK1ENPP1
SCHEMBL10407277 0.77 TSHR (0.50) TSHRALDH1A1HSD17B10PAX2MEN1
SCHEMBL10407276 0.77 TSHR (0.50) TSHRALDH1A1HSD17B10PAX2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP claimed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US claimed
US-4078937-A SULFUR, HYDROXYTETRAAZAINDENE FUJI PHOTO FILM CO., LTD. (JA) 1978-03-14 US claimed
EP-2660632-A1 FUNCTIONAL FILM, FILM MIRROR, AND REFLECTING DEVICE FOR SOLAR THERMAL POWER GENERATION Konica Minolta, Inc. (JP) 2013-11-06 EP disclosed
US-20130279001-A1 FUNCTIONAL FILM, FILM MIRROR, AND REFLECTING DEVICE FOR SOLAR THERMAL POWER GENERATION Konica Minolta, Inc. (JP) 2013-10-24 US disclosed
EP-1217432-B1 Silver halide photographic light-sensitive material and method for processing the same FUJIFILM CORP (JP) 2007-08-15 EP disclosed
US-6593076-B2 Controlling concentration of silver hlaide emulsion and organic silver salt KONICA CORPORATION (JP) 2003-07-15 US disclosed
EP-1109060-B1 Silver halide photographic element EASTMAN KODAK CO (US) 2003-06-04 EP disclosed
US-6544718-B2 Hydrophilic colloid layer includes a disulfide or dimercapto compound of given formula; for photomechanical plate-making that exhibits ultrahigh-contrast photographic characteristics FUJI PHOTO FILM CO., LTD. (JP) 2003-04-08 US disclosed
US-20030022113-A1 Silver halide photographic light-sensitive material and method for processing same FUJI PHOTO FILM CO., LTD. 2003-01-30 US disclosed
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP disclosed
US-4617258-A WATER SOLUBLE GROUP 8 COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-10-14 US disclosed
US-4565778-A COMPRISING CORE/SHELL GRAINS OF SILVER IODOBROMIDE REPENED BY A LABILE SELENIUM COMPOUND;PHOTOSENSITIVITY;ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-01-21 US disclosed
US-4542094-A HYDROXYTETRAZAINDENES AND MERCAPTO-NITROGENCONTAINING HETEROCYLIC COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-17 US disclosed
EP-0122125-A1 Silver halide emulsion KONICA CORPORATION (JP) 1984-10-17 EP disclosed
US-4477561-A PLATIUM, DALLADIUM, RHODIUM, IRIDIUM AND OSMIUM SALTS; LIGHT SENSITIVE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-10-16 US disclosed
EP-0121435-A1 Silver halide photographic materials KONICA CORPORATION (JP) 1984-10-10 EP disclosed
EP-0107488-A2 Silver halide emulsions KONICA CORPORATION (JP) 1984-05-02 EP disclosed
EP-0091788-A2 Silver halide photographic material KONICA CORPORATION (JP) 1983-10-19 EP disclosed
EP-0089101-A2 Direct positive image-forming process KONICA CORPORATION (JP) 1983-09-21 EP disclosed