Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199382 | 0.86 | CHRNB2 (0.42) | TAS1R3TAS1R1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3032255 | 0.83 | TAS1R3 (0.43) | TAS1R3TAS1R1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18154475 | 0.81 | TAS1R3 (0.44) | TAS1R3TAS1R1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5198675 | 0.80 | TAS1R3 (0.37) | TAS1R3TAS1R1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6286602 | 0.78 | TAS1R3 (0.42) | TAS1R3TAS1R1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6695234 | 0.78 | TAS1R3 (0.39) | TAS1R3TAS1R1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6695340 | 0.77 | TAS1R3 (0.41) | TAS1R3TAS1R1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6287585 | 0.77 | GPR88 (0.41) | TAS1R3TAS1R1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6699138 | 0.75 | TAS1R3 (0.40) | TAS1R3TAS1R1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7920138 | 0.75 | CHRNB2 (0.45) | TAS1R3TAS1R1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481981-B1 | Styrene hypophosphite adduct, preparation thereof and use | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2007-08-15 | — | — | EP | disclosed |
| EP-1481981-A2 | Styrene hypophosphite adduct, preparation thereof and use | Clariant GmbH (DE) | 2004-12-01 | — | — | EP | disclosed |