SCHEMBL7920138

SCHEMBL7920138

C=Cc1ccc(OC(C)CC)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 2/20 0.45
CHRNA7 P36544 2/20 0.45
CHRNB4 P30926 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNA4 P43681 1/20 0.45
ALDH1A1 P00352 2/20 0.42
ALDH1A3 P47895 1/20 0.41
HDAC8 Q9BY41 3/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC2 Q92769 2/20 0.40
ACACB O00763 3/20 0.38
MAPT P10636 1/20 0.36
TAS1R3 Q7RTX0 2/20 0.35
TAS1R1 Q7RTX1 2/20 0.35
SIRT2 Q8IXJ6 1/20 0.34
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
TSHR P16473 1/20 0.33
NPC1 O15118 1/20 0.33
MTOR P42345 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3032255 0.85 TAS1R3 (0.43) CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4
SCHEMBL14000539 0.84 HDAC1 (0.47) CHRNB2CHRNA7ALDH1A3HDAC8HDAC1
SCHEMBL12410173 0.84 HDAC1 (0.47) CHRNB2CHRNA7ALDH1A3HDAC8HDAC1
SCHEMBL122883 0.83 ACACB (0.45) ALDH1A3HDAC8HDAC1HDAC2ACACB
SCHEMBL10204601 0.83 ALDH1A1 (0.41) CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4
SCHEMBL6287585 0.82 GPR88 (0.41) CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4
SCHEMBL29015274 0.82 TDP1 (0.40) CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4
SCHEMBL6270668 0.81 CHRNB2 (0.42) CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4
SCHEMBL5199382 0.81 CHRNB2 (0.42) CHRNB2CHRNA7CHRNB4CHRNA3CHRNA4
SCHEMBL16353393 0.81 ALDH1A3 (0.66) ALDH1A1ALDH1A3HDAC8HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107810179-B Sulfonic acid derivative compounds as photoacid generators in resist applications 贺利氏电子化工有限责任公司 2021-10-22 CN disclosed
US-10976658-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications HERAEUS EPURIO LLC (US) 2021-04-13 US disclosed
US-20200089110-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2020-03-19 US disclosed
US-20180208728-A1 NANOPOROUS LYOTROPIC LIQUID CRYSTAL POLYMER MEMBRANES WITH REVERSIBLY TUNED PORE SIZE AND SELECTIVITY, AND METHODS USING SAME NATIONAL SCIENCE FOUNDATION 2018-07-26 US disclosed
CN-107810179-A SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS 贺利氏贵金属北美代顿有限责任公司 2018-03-16 CN disclosed
WO-2017034814-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS Heraeus Precious Metals North America Daychem LLC (US) 2017-03-02 WO disclosed
WO-2017034814-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS Heraeus Precious Metals North America Daychem LLC (US) 2017-03-02 WO disclosed
EP-2468799-B1 PROCESS FOR PRODUCTION OF MODIFIED POLYSILOXANE COMPOUND NIPPON SODA CO (JP) 2014-04-30 EP disclosed
US-8420744-B2 Process for the production of modified polysiloxanes NIPPON SODA CO., LTD. (JP) 2013-04-16 US disclosed
EP-2468799-A1 PROCESS FOR PRODUCTION OF MODIFIED POLYSILOXANE COMPOUND Nippon Soda Co., Ltd. (JP) 2012-06-27 EP disclosed
US-20120136122-A1 PROCESS FOR PRODUCTION OF MODIFIED POLYSILOXANE COMPOUND NIPPON SODA CO., LTD. (JP) 2012-05-31 US disclosed
US-6218485-B1 LIVING ANIONIC POLYMERIZATION USING AN ORGANIC ALKALI METAL AND/OR AN ALKALI METAL AS A POLYMERIZATION INITIATOR, WHEREIN A TARGET MOLECULAR WEIGHT IS OBTAINED BY ADDING THE COMPOUND DIVIDED INTO MULTIPLE STEPS. NIPPON SODA CO., LTD. (JP) 2001-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10976658-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications ALAD, MPST, ASIC1 CHRNB2 4514/4885CHRNA7 4139/4885CHRNB4 4483/4885
US-20200089110-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS ALAD, MPST, ASIC1 CHRNB2 4514/4885CHRNA7 4139/4885CHRNB4 4483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.