Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15686614 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9AALDH1A1HPGDCHRNB2 | |
| SCHEMBL7993058 | 0.76 | KMT2A (0.46) | SMN1; SMN2RAB9AALDH1A1HPGDCHRNB2 | |
| SCHEMBL7993053 | 0.76 | KMT2A (0.46) | SMN1; SMN2RAB9AALDH1A1HPGDCHRNB2 | |
| SCHEMBL5194448 | 0.76 | RAB9A (0.42) | SMN1; SMN2RAB9AALDH1A1HPGDCHRNB2 | |
| SCHEMBL8324218 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1CHRNB2CHRNA4CHRNA1 | |
| Imidacloprid SCHEMBL15474899 | 0.74 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1CHRNB2CHRNA4CHRNA1 | |
| Imidacloprid SCHEMBL15284816 | 0.74 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL5194738 | 0.74 | RAB9A (0.41) | SMN1; SMN2RAB9AALDH1A1HPGDCHRNB2 | |
| SCHEMBL5196343 | 0.74 | RAB9A (0.41) | SMN1; SMN2RAB9AALDH1A1HPGDCHRNB2 | |
| Imidacloprid SCHEMBL22278 | 0.74 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1CHRNB2CHRNA4CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348705-B1 | Alkylene-tethered bis-nitroiminoimidazolidines, process for preparing the same, and insecticides containing the same | PRESIDENT OF GIFU UNIVERSITY (JP) | 2007-03-21 | — | — | EP | disclosed |
| US-6875778-B2 | Alkylene-tethered bis-nitroiminoimidazolidines, process for preparing the same, and insecticides containing the same | GIFU UNIVERSITY | 2005-04-05 | — | — | US | disclosed |
| US-20030220305-A1 | Alkylene-tethered bis-nitroiminoimidazolidines, process for preparing the same, and insecticides containing the same | GIFU UNIVERSITY | 2003-11-27 | — | — | US | disclosed |
| EP-1348705-A2 | Alkylene-tethered bis-nitroiminoimidazolidines, process for preparing the same, and insecticides containing the same | President of Gifu University (JP) | 2003-10-01 | — | — | EP | disclosed |
| US-6566528-B1 | Reacting 2-chloro-3-chloromethyl-5-methyl pyridine and 2-nitroimino-1,3-diazacyclopentane in the presence of a base and an organic solvent; insecticides that act at the nicotinic acetylcholine receptor | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-05-20 | — | — | US | disclosed |
| EP-1306374-A1 | 1-(2-chloro-5-methyl-3-pyridylmethyl)-2-nitroiminoimadozolidine and a process for the preparation thereof | Council of Scientific and Industrial Research (IN) | 2003-05-02 | — | — | EP | disclosed |
| US-20030083350-A1 | 1-(2-CHLORO-5-METHYL-3-PYRIDYLMETHYL)-2-NITROIMINIOMIDAZOLIDINE AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220305-A1 | Alkylene-tethered bis-nitroiminoimidazolidines, process for preparing the same, and insecticides containing the same | KCNH1, KCNH3, KCNH2 | SMN1; SMN2 574/4885RAB9A 1232/4885ALDH1A1 1406/4885 |
| US-20030083350-A1 | 1-(2-CHLORO-5-METHYL-3-PYRIDYLMETHYL)-2-NITROIMINIOMIDAZOLIDINE AND PROCESS FOR THE PREPARATION THEREOF | CYP1B1, CYP2C9, CYP1A1 | SMN1; SMN2 1941/4885RAB9A 1545/4885ALDH1A1 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.