Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558282 | 0.89 | FUCA1 (0.60) | CCR5ALDH1A1FUCA1SLC18A3SIGMAR1 | |
| SCHEMBL11558271 | 0.89 | FUCA1 (0.60) | CCR5ALDH1A1FUCA1SLC18A3SIGMAR1 | |
| SCHEMBL11558275 | 0.89 | FUCA1 (0.60) | CCR5ALDH1A1FUCA1SLC18A3SIGMAR1 | |
| SCHEMBL6624318 | 0.87 | FUCA1 (0.71) | CCR5ALDH1A1FUCA1SIGMAR1KDM1A | |
| SCHEMBL5157969 | 0.83 | FUCA1 (0.66) | ALDH1A1FUCA1SLC18A3SIGMAR1ACHE | |
| SCHEMBL5157349 | 0.83 | FUCA1 (0.66) | ALDH1A1FUCA1SLC18A3SIGMAR1ACHE | |
| SCHEMBL3557156 | 0.81 | CCR5 (0.57) | CCR5ALDH1A1SIGMAR1ACHEBCHE | |
| SCHEMBL3551204 | 0.81 | CCR5 (0.57) | CCR5ALDH1A1SIGMAR1ACHEBCHE | |
| SCHEMBL3559501 | 0.81 | CCR5 (0.57) | CCR5ALDH1A1SIGMAR1ACHEBCHE | |
| SCHEMBL3559498 | 0.81 | CCR5 (0.57) | CCR5ALDH1A1SIGMAR1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790636-A1 | PIPERIDINE DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-05-30 | — | — | EP | disclosed |
| US-20060142337-A1 | Piperidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142337-A1 | Piperidine derivative and use thereof | AR, AHR, ARNT | CCR5 1472/4885ALDH1A1 26/4885FUCA1 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.