Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558282 | 1.00 | FUCA1 (0.60) | FUCA1ALDH1A1SLC18A3HTTCCR5 | |
| SCHEMBL11558275 | 1.00 | FUCA1 (0.60) | FUCA1ALDH1A1SLC18A3HTTCCR5 | |
| SCHEMBL6042249 | 0.91 | ACHE (0.56) | FUCA1ALDH1A1SLC18A3HTTACHE | |
| SCHEMBL6042732 | 0.90 | RORC (0.58) | FUCA1ALDH1A1SLC18A3HTTACHE | |
| SCHEMBL6041900 | 0.90 | ACHE (0.55) | FUCA1ALDH1A1SLC18A3HTTACHE | |
| SCHEMBL6041781 | 0.90 | SLC18A3 (0.58) | FUCA1ALDH1A1SLC18A3ACHEBCHE | |
| SCHEMBL6043310 | 0.90 | FUCA1 (0.53) | FUCA1ALDH1A1SLC18A3HTTGBA1 | |
| SCHEMBL5198451 | 0.89 | CCR5 (0.57) | FUCA1ALDH1A1SLC18A3CCR5ACHE | |
| SCHEMBL6043029 | 0.87 | FUCA1 (0.50) | FUCA1ALDH1A1SLC18A3HTTCCR5 | |
| SCHEMBL6041336 | 0.87 | DRD2 (0.67) | FUCA1ALDH1A1SLC18A3HTTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132710-A | DIURETICS, ANOREXICS, ANTIDEPRESSANTS, ANTICONVULSANTS, & ANTIHYPERTENSIVE AGENTS | AYERST, MCKENNA AND HARRISON, LTD. (CA) | 1979-01-02 | — | — | US | disclosed |