Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.71 |
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 3/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MTAP | Q13126 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571278 | 0.89 | CCR5 (0.60) | FUCA1CCR5RORCKDM1AS1PR1 | |
| SCHEMBL5198451 | 0.87 | CCR5 (0.57) | FUCA1CCR5KDM1AALDH1A1SIGMAR1 | |
| SCHEMBL84802 | 0.87 | FUCA1 (0.85) | FUCA1GBA1ALDH1A1S1PR1S1PR5 | |
| SCHEMBL5155562 | 0.87 | FUCA1 (0.85) | FUCA1GBA1ALDH1A1S1PR1S1PR5 | |
| SCHEMBL20017877 | 0.87 | FUCA1 (0.85) | FUCA1GBA1ALDH1A1S1PR1S1PR5 | |
| SCHEMBL562632 | 0.87 | FUCA1 (0.85) | FUCA1GBA1ALDH1A1S1PR1S1PR5 | |
| SCHEMBL71063 | 0.87 | FUCA1 (0.85) | FUCA1GBA1ALDH1A1S1PR1S1PR5 | |
| Hydrochloric Acid SCHEMBL10840201 | 0.85 | FUCA1 (0.81) | FUCA1GBA1ALDH1A1S1PR1S1PR5 | |
| SCHEMBL11558275 | 0.85 | FUCA1 (0.60) | FUCA1GBA1CCR5KDM1AALDH1A1 | |
| SCHEMBL11558271 | 0.85 | FUCA1 (0.60) | FUCA1GBA1CCR5KDM1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985664-B1 | Method of producing pyrrolidine derivatives | TORAY FINECHEMICALS CO LTD (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6479668-B1 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2002-11-12 | — | — | US | disclosed |
| US-6130338-A | OXIDATING THE CORRESPONDING 3-PYRROLINE COMPOUND TO GIVE AN EPOXYPYRROLIDINE COMPOUND | TORAY INDUSTRIES, INC. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0985664-A2 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |