Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499794 | 0.87 | POLB (0.57) | POLBLMNAL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL2320404 | 0.81 | FAAH (0.59) | LMNAL3MBTL1ALDH1A1NPSR1MAPK1 | |
| SCHEMBL5199852 | 0.81 | L3MBTL1 (0.40) | POLBLMNAL3MBTL1ALDH1A1TSHR | |
| SCHEMBL5502790 | 0.80 | SMN1; SMN2 (0.47) | LMNAL3MBTL1TSHRFAAHSMN1; SMN2 | |
| SCHEMBL844472 | 0.80 | SMN1; SMN2 (0.57) | POLBLMNAL3MBTL1ALDH1A1TSHR | |
| SCHEMBL14040614 | 0.80 | SMN1; SMN2 (0.57) | POLBLMNAL3MBTL1ALDH1A1TSHR | |
| SCHEMBL5088792 | 0.80 | CTSA (0.51) | POLBALDH1A1MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL5085765 | 0.78 | SMN1; SMN2 (0.50) | POLBLMNAL3MBTL1MAPK1FAAH | |
| SCHEMBL5504022 | 0.77 | SMN1; SMN2 (0.42) | POLBLMNAL3MBTL1ALDH1A1TSHR | |
| SCHEMBL3663293 | 0.77 | FAAH (0.58) | LMNAL3MBTL1NPSR1MAPK1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576179-A4 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS | IRM LLC (BM) | 2007-06-06 | — | — | EP | disclosed |
| EP-1576179-A2 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS | IRM LLC (BM) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004050895-A2 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS | IRM LLC (BM) | 2004-06-17 | — | — | WO | disclosed |