Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195599 | 0.81 | EPHX1 (0.49) | — | |
| SCHEMBL5197653 | 0.79 | MAPT (0.39) | MAPTMAPK1EPHX2ATML3MBTL1 | |
| SCHEMBL5195333 | 0.79 | MAPT (0.39) | MAPTMAPK1EPHX2ATML3MBTL1 | |
| SCHEMBL5197473 | 0.77 | MC4R (0.42) | — | |
| SCHEMBL5456713 | 0.77 | SLC6A4 (0.39) | ATMADH1CADH1A | |
| SCHEMBL27564719 | 0.74 | ALDH1A1 (0.44) | MAPTEPHX2ATMADH1CADH1A | |
| SCHEMBL6418241 | 0.72 | KMT2A (0.45) | MAPTATML3MBTL1 | |
| SCHEMBL5195891 | 0.72 | HTT (0.41) | MAPTMAPK1EPHX2ATML3MBTL1 | |
| SCHEMBL1311214 | 0.71 | OPRD1 (0.40) | HTR2A | |
| SCHEMBL6435389 | 0.70 | KMT2A (0.43) | MAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786809-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | Sanofi-Aventis (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021656-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | disclosed |