Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195333 | 1.00 | MAPT (0.39) | MAPTMAPK1ADH1CADH1AEPHX2 | |
| SCHEMBL10778320 | 0.85 | ADH1A (0.45) | ADH1CADH1AL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL5446083 | 0.80 | EPHX1 (0.51) | HPGD | |
| SCHEMBL5456521 | 0.80 | EPHX1 (0.51) | HPGD | |
| SCHEMBL5199047 | 0.79 | MAPT (0.38) | MAPTMAPK1ADH1CADH1AEPHX2 | |
| SCHEMBL5244334 | 0.78 | USP2 (0.33) | ADH1CADH1AL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL27564719 | 0.76 | ALDH1A1 (0.44) | MAPTADH1CADH1AEPHX2ATM | |
| SCHEMBL5459487 | 0.76 | SLC6A4 (0.40) | ADH1CADH1AL3MBTL1NPSR1 | |
| SCHEMBL5449617 | 0.76 | SLC6A4 (0.40) | ADH1CADH1AL3MBTL1NPSR1 | |
| SCHEMBL6418241 | 0.74 | KMT2A (0.45) | MAPTL3MBTL1ATMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786809-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | Sanofi-Aventis (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021656-A2 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONISTS | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | disclosed |