Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199047 | 0.77 | MAPT (0.38) | ADH1CADH1AATM | |
| SCHEMBL5449617 | 0.77 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3KCNH2ADH1C | |
| SCHEMBL5459487 | 0.77 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3KCNH2ADH1C | |
| SCHEMBL2278722 | 0.74 | SLC6A2 (0.54) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL13622839 | 0.73 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 | |
| SCHEMBL2275673 | 0.72 | TSHR (0.55) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 | |
| SCHEMBL27624686 | 0.72 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 | |
| SCHEMBL16795227 | 0.71 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 | |
| SCHEMBL8003405 | 0.71 | KMT2A (0.43) | SLC6A4SLC6A2SLC6A3KCNH2TSHR | |
| SCHEMBL2281424 | 0.71 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2ADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039941-A | Aminopiperidine derivatives, their preparation and use as melanocortin receptor agonists | SANOFI AVENTIS (FR) | 2007-09-19 | — | — | CN | disclosed |
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | MC4R, MC5R, TAAR5 | SLC6A4 728/4885SLC6A2 276/4885SLC6A3 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.