SCHEMBL519935

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL519010	0.77	ALDH1A1 (0.54)	ALDH1A1MAPTMAPK1HPGDKDM4E
	SCHEMBL518953	0.76	RAB9A (0.48)	ALDH1A1MAPTMAPK1MEN1KMT2A
	SCHEMBL518603	0.76	MAPT (0.50)	ALDH1A1MAPTMAPK1MEN1KMT2A
	SCHEMBL519170	0.75	ALDH1A1 (0.70)	ALDH1A1MAPTMAPK1MEN1KMT2A
	SCHEMBL519257	0.74	MAPT (0.56)	ALDH1A1MAPTMAPK1MEN1KMT2A
	SCHEMBL31465667	0.74	ALDH1A1 (0.56)	ALDH1A1MAPTFABP3FABP4FABP5
	SCHEMBL519266	0.73	L3MBTL1 (0.45)	ALDH1A1MAPTMAPK1KMT2AKDM4E
	SCHEMBL518930	0.73	ALDH1A1 (0.56)	ALDH1A1MAPTMAPK1MEN1KMT2A
	SCHEMBL99181	0.73	ALDH1A1 (0.59)	ALDH1A1MAPTMEN1KMT2ACYP2C9
	SCHEMBL7790157	0.72	MAPT (0.43)	ALDH1A1MAPTMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.