Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 7/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289900 | 0.85 | USP7 (0.41) | USP7CSNK1A1CLK4HTTKDM4E | |
| SCHEMBL20489548 | 0.84 | USP7 (0.40) | USP7CSNK1A1CLK4HTTKDM4E | |
| SCHEMBL8320187 | 0.75 | MAPK1 (0.42) | USP7CSNK1A1CLK4HTTKDM4E | |
| SCHEMBL8321298 | 0.73 | KDM4E (0.45) | CSNK1A1CLK4HTTKDM4EKMT2A | |
| SCHEMBL1542472 | 0.73 | NOS2 (0.47) | USP7NOS3NOS2 | |
| SCHEMBL21736855 | 0.73 | KDM5A (0.39) | USP7KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL21753704 | 0.72 | ALDH1A1 (0.37) | USP7HTTKDM4EKMT2AMEN1 | |
| SCHEMBL12844135 | 0.72 | CSNK1A1 (0.55) | CSNK1A1CLK4HTTKDM4EKMT2A | |
| SCHEMBL27354358 | 0.72 | USP7 (0.36) | USP7CSNK1A1CLK4HTTKDM4E | |
| SCHEMBL28291326 | 0.70 | CSNK1A1 (0.37) | CSNK1A1CLK4HTTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075661-B1 | LIGAND BINDING ASSAY AND KIT WITH A SEPARATION ZONE FOR DISTURBING SAMPLE COMPONENTS | MAIIA AB (SE) | 2007-08-22 | — | — | EP | disclosed |
| EP-1467210-A1 | Method with separation and kit for use in the method | PHARMACIA DIAGNOSTICS AB (SE) | 2004-10-13 | — | — | EP | disclosed |
| US-6737278-B1 | FLOW MATRIX CONTAINS SEPARATION ZONES TO RETARD OR SEPARATE A COMPONENT CAPABLE OF DISTURBINGOR INFLUENCING THE SIGNAL FROM THE SIGNAL COMPLEX | PHARMACIA & UPJOHN DIAGNOSTIC AB (SE) | 2004-05-18 | — | — | US | disclosed |
| US-20040023412-A1 | Ligand binding assay and kit with a separation zone for disturbing analytes | PHARMACIA & UPJOHN DIAGNOSTICS AB. | 2004-02-05 | — | — | US | disclosed |
| EP-1075661-A1 | LIGAND BINDING ASSAY AND KIT WITH A SEPARATION ZONE FOR DISTURBING ANALYTES | PHARMACIA AB (SE) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999060402-A1 | LIGAND BINDING ASSAY AND KIT WITH A SEPARATION ZONE FOR DISTURBING ANALYTES | PHARMACIA & UPJOHN DIAGNOSTICS AB (SE) | 1999-11-25 | — | — | WO | disclosed |