Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200055 | 0.81 | CA1 (0.33) | CYP1A2CA1CA2CA4KMT2A | |
| SCHEMBL17746680 | 0.78 | CRBN (0.37) | CYP1A2CA1CA2CA4CYP19A1 | |
| SCHEMBL14679897 | 0.72 | OTUD7B (0.36) | CYP1A2 | |
| SCHEMBL19370759 | 0.71 | CRBN (0.34) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL31273056 | 0.71 | CYP1A2 (0.34) | CYP1A2 | |
| SCHEMBL2774682 | 0.70 | CRBN (0.32) | — | |
| SCHEMBL1786726 | 0.70 | — | — | |
| SCHEMBL3397460 | 0.70 | — | — | |
| SCHEMBL13484692 | 0.68 | ALDH1A1 (0.39) | KMT2AATMMEN1ALDH1A1MAPT | |
| SCHEMBL537099 | 0.68 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411110-B1 | Spiro compounds as perfuming ingredients | FIRMENICH & CIE (CH) | 2007-08-22 | — | — | EP | disclosed |
| US-7256170-B2 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2007-08-14 | — | — | US | disclosed |
| EP-1411110-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | SORD, PIR, AKR1C4 | CYP1A2 69/4885CA1 3465/4885CA2 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.