Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077339 | 0.86 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL5203734 | 0.83 | MEN1 (0.34) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8452305 | 0.83 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL6957304 | 0.80 | SLC6A2 (0.50) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL8290900 | 0.80 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL7751548 | 0.77 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL8291781 | 0.75 | SLC6A3 (0.46) | SLC6A4SLC6A2SLC6A3CYP2D6KDM4C | |
| SCHEMBL7947168 | 0.75 | SLC6A2 (0.48) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL6494323 | 0.74 | CCR5 (0.37) | NPC1MEN1KMT2AL3MBTL1TACR1 | |
| SCHEMBL9027925 | 0.74 | SLC6A2 (0.67) | SLC6A4SLC6A2SLC6A3CYP2D6TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150970-B1 | (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI AVENTIS (FR) | 2007-08-22 | — | — | EP | disclosed |
| US-6951940-B2 | Piperidine derivatives, process for obtaining them and pharmaceutical compositions containing them | SANOFI-AVENTIS (FR) | 2005-10-04 | — | — | US | disclosed |
| US-20040072840-A1 | Novel piperidine derivatives, process for obtaining them and pharmaceutical compositions containing them | SANOFI-AVENTIS (FR) | 2004-04-15 | — | — | US | disclosed |
| US-6642233-B1 | Strong affinity and high selectivity for the human NK1 receptors of substance P. | SANOFI-SYNTHELABO (FR) | 2003-11-04 | — | — | US | disclosed |
| EP-1150970-A1 | (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Sanofi-Aventis (FR) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047572-A1 | (1-PHENACY-3-PHENYL-3-PIPERIDYLETHYL)PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2000-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072840-A1 | Novel piperidine derivatives, process for obtaining them and pharmaceutical compositions containing them | TACR1, TACR2, KCNJ11 | SLC6A4 1027/4885SLC6A2 1874/4885SLC6A3 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.