Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871014 | 0.88 | CCR5 (0.47) | OPRM1CCR5MEN1KMT2ACCR4 | |
| SCHEMBL4081913 | 0.88 | DRD2 (0.43) | OPRM1DRD2SLC6A4HTR2AHTR7 | |
| Oxalic Acid SCHEMBL5871140 | 0.87 | CCR5 (0.49) | OPRM1CCR5MEN1KMT2ACCR4 | |
| SCHEMBL5871942 | 0.87 | HTR1A (0.48) | OPRM1DRD2SLC6A4CCR5HTR2A | |
| SCHEMBL5871701 | 0.86 | DRD2 (0.44) | OPRM1DRD2SLC6A4HTR2AHTR7 | |
| Oxalic Acid SCHEMBL5871682 | 0.86 | CCR5 (0.47) | OPRM1CCR5KCNH2MEN1KMT2A | |
| SCHEMBL5871734 | 0.85 | SLC6A4 (0.46) | OPRM1DRD2SLC6A4HTR2AHTR7 | |
| Oxalic Acid SCHEMBL5871218 | 0.85 | HTR1A (0.46) | OPRM1DRD2SLC6A4CCR5HTR2A | |
| SCHEMBL4076926 | 0.84 | HTR2A (0.44) | OPRM1DRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL5871274 | 0.83 | CCR3 (0.41) | OPRM1DRD2SLC6A4HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179532-B1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | EISAI R&D MAN CO LTD (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6573384-B1 | 1,4-substituted cyclic amine compound which is useful as a pharmaceutical, and an intermediate for the process | EISAI CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1179532-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR | Eisai Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |