SCHEMBL4076926

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5871543	0.91	DRD2 (0.44)	HTR2ADRD2SLC6A4CACNA1GHTR1A
	SCHEMBL5871619	0.90	DRD2 (0.40)	DRD2SLC6A4CACNA1GHTR1AHTR1D
	SCHEMBL5871553	0.90	DRD2 (0.40)	DRD2SLC6A4CACNA1GHTR1AHTR1D
	SCHEMBL5871029	0.90	HTR1A (0.44)	HTR2AHTR2CHTR2BDRD2HTR1A
	SCHEMBL5871660	0.89	KMT2A (0.39)	DRD2SLC6A4CACNA1GHTR1AHTR1D
	SCHEMBL4073394	0.88	DRD2 (0.41)	DRD2SLC6A4CACNA1GHTR1AHTR1D
	SCHEMBL5871544	0.87	HTR1A (0.50)	HTR2AHTR2CHTR2BDRD2SLC6A4
	SCHEMBL5871701	0.86	DRD2 (0.44)	HTR2ADRD2SLC6A4CACNA1GHTR1A
	SCHEMBL5872025	0.86	CACNA1G (0.45)	HTR2AHTR2CHTR2BDRD2SLC6A4
	SCHEMBL4081913	0.86	DRD2 (0.43)	HTR2ADRD2SLC6A4CACNA1GHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.